PUBLICATIONS
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List of Services
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Selected Publications over the last 5 years
Selected Publications over the last 5 years
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Building consensus on definition and nomenclature of hepatic, pancreatic, and biliary organoidsList Item 1
Marsee A, Roos FJM, Verstegen MMA; HPB Organoid Consortium; Gehart H, de Koning E, Lemaigre F, Forbes SJ, Peng WC, Huch M, Takebe T, Vallier L, Clevers H, van der Laan LJW, Spee B.
Cell Stem Cell. 2021 May 6;28(5):816-832.
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Regional Differences in Human Biliary Tissues and Corresponding In Vitro-Derived OrganoidsList Item 2
Rimland CA, Tilson SG, Morell CM, Tomaz RA, Lu WY, Adams SE, Georgakopoulos N, Otaizo-Carrasquero F, Myers TG, Ferdinand JR, Gieseck RL 3rd, Sampaziotis F, Tysoe OC, Ross A, Kraiczy JM, Wesley B, Muraro D, Zilbauer M, Oniscu GC, Hannan NRF, Forbes SJ, Saeb-Parsy K, Wynn TA, Vallier L.
Hepatology. 2021 Jan;73(1):247-267.
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hiPSC hepatocyte model demonstrates the role of unfolded protein response and inflammatory networks in α1-antitrypsin deficiencyList Item 3
Charis-Patricia Segeritz, Sheikh Tamir Rashid, Miguel Cardoso de Brito, Maria Paola Serra, Adriana Ordonez, Carola Maria Morell, Joseph E Kaserman, Pedro Madrigal, Nicholas R F Hannan, Laurent Gatto, Lu Tan, Andrew A Wilson, Kathryn Lilley, Stefan J Marciniak, Bibek Gooptu, David A Lomas, Ludovic Vallier.
J Hepatol. 2018 Oct;69(4):851-860.
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Reconstruction of the mouse extrahepatic biliary tree using primary human extrahepatic cholangiocyte organoidsList Item 4
Fotios Sampaziotis, Alexander W Justin, Olivia C Tysoe, Stephen Sawiak, Edmund M Godfrey, Sara S Upponi, Richard L Gieseck, Miguel Cardoso de Brito, Natalie Lie Berntsen, María J Gómez-Vázquez, Daniel Ortmann, Loukia Yiangou, Alexander Ross, Johannes Bargehr, Alessandro Bertero, Mariëlle C F Zonneveld, Marianne T Pedersen, Matthias Pawlowski, Laura Valestrand, Pedro Madrigal, Nikitas Georgakopoulos, Negar Pirmadjid, Gregor M Skeldon, John Casey, Wenmiao Shu, Paulina M Materek, Kirsten E Snijders, Stephanie E Brown, Casey A Rimland, Ingrid Simonic, Susan E Davies, Kim B Jensen, Matthias Zilbauer, William T H Gelson, Graeme J Alexander, Sanjay Sinha, Nicholas R F Hannan, Thomas A Wynn, Tom H Karlsen, Espen Melum, Athina E Markaki, Kourosh Saeb-Parsy, Ludovic Vallier.
Nat Med. 2017 Aug;23(8):954-963.
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Directed differentiation of human induced pluripotent stem cells into functional cholangiocyte-like cells
Fotios Sampaziotis, Miguel Cardoso de Brito, Imbisaat Geti, Alessandro Bertero, Nicholas RF Hannan, Ludovic Vallier.
Nat Protoc. 2017 Apr;12(4):814-827.
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Cholangiocytes derived from human induced pluripotent stem cells for disease modeling and drug validation
Fotios Sampaziotis, Miguel Cardoso de Brito, Pedro Madrigal, Alessandro Bertero, Kourosh Saeb-Parsy, Filipa AC Soares, Elisabeth Schrumpf, Espen Melum, Tom H Karlsen, J Andrew Bradley, William TH Gelson, Susan Davies, Alastair Baker, Arthur Kaser, Graeme J Alexander, Nicholas RF Hannan, Ludovic Vallier
Nat Biotechnol. 2015 Aug;33(8):845-852.
